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Determining the degree of severity of the interlobular and periductal fibrosis of the pancreas in patients with chronic pancreatitis

Індентифікаційний номер: Offers
Опубліковано: 08 December 2014 Кінцева дата: 08 February 2018
Країна: Україна

The developer proposes a method for determining the severity of the interlobular and periductal fibrosis in the pancreas biopsies by immunohistochemistry complex and morphometric analysis of digital images using the program ImageJ, which improves the accuracy of diagnosis of the severity of fibrosis of the pancreas in patients with chronic pancreatitis of different genesis.


Ключові слова:

Medicine, health care, diagnosis, a diagnosis


Опис пропозиції

Developed a method for determining the severity of the interlobular and periductal fibrosis in the pancreas biopsies by immunohistochemistry the expression of α-smooth muscle actin isoforms (α-SMA) activated stellate cells and morphometric fototsifrovogo determining the area of these cells in the ImageJ program allows you to accurately set the area and the degree of fibrosis in various gistotopografichnih areas of the pancreas.

Тип технології

Biotechnology
Процес

Сфера застосування

The method used in the pathological diagnosis. Medicine, pathological anatomy, surgery, gastroenterology.

Технічні та економічні переваги

Efficiency and the degree of accuracy of diagnosis of fibrosis of the pancreas in chronic pancreatitis various genesis increased on average by 34%.

Iнноваційні аспекти

The introduction of technology can accurately determine the area of fibrosis in various areas of the pancreas gistotopograficheskih for immunohistochemical expression of α-SMA and its degree by fototsifrovoy morphometry intensity α-SMA expression in the program ImageJ without using special laboratory equipment

Де була представлена технологія

The technology is implemented and tested in Zaporizhzhya, Chernihiv, Vinnytsia, Dnipropetrovsk, Odessa, Sumy, Poltava and Lviv regional pathological Bureau (diagnostic accuracy degree of severity of fibrosis increased by an average of 34%).

Поточна стадія: Є результати експериментальних досліджень
Впроваджено
Статус прав інтелектуальної властності: Заявка на патент

Умови співпраці:

Тип організації:

research organization

Регіони: Країни СНД
Східна Європа
Центральна Європа
Тип співпраці:

Joint further development


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